MBD - Metabolic Bone Disease Info

[ToxicSiren]

xxx

[kevin d]

good post i seen alot off people on hear say you dont neeed a bulb for leos but when i put one in i notice a difrence with my leo straight away and help with the mbd worth geting a bulb find that she is so more active

[ToxicSiren]

Originally Posted by kevin d

good post i seen alot off people on hear say you dont neeed a bulb for leos but when i put one in i notice a difrence with my leo straight away and help with the mbd worth geting a bulb find that she is so more active

For reps with MBD i always recomend a uv bulb even if its only a 2% as the extra d3 from the uv will help with absorbtion of calcium therfore helping the MBD. x

[Mitchellz]

Ummm my baby leo i got a month ago when she lifts her feet up, they like shake, then she takes them down and their alright...Is that normal for a baby to do that? Shes eating and everything fine and drinking

[kevin d]

mbd mine does the same

[ToxicSiren]

Originally Posted by Mitchellz

Ummm my baby leo i got a month ago when she lifts her feet up, they like shake, then she takes them down and their alright...Is that normal for a baby to do that? Shes eating and everything fine and drinking

Shaking can be a a sign of MBD, does she look to have twisted or rubber legs? Does she have calcium and d3 like nutrobal in her diet? x

[James D]

I agree that this thread is a good idea, but there are a couple of things that could be added to it....

Originally Posted by ToxicSiren

D3 can come in forms of UVA/UVB light or in powders such as nutrobal

UVA does not control the biosynthesis of vitamin D3 at all as far as I'm aware, although UVB is very important.

Originally Posted by ToxicSiren

Inadequate protein

Could you explain how this would cause MBD?
I've never heard of this being a cause and can't think how it would result in this disease...

Originally Posted by ToxicSiren

Cool temperatures as they impair digestion and therefore calcium absorption.

Although low temps. will result in less efficient digestion, this is not why it can result in MBD.
The biosynthesis of vitamin D3 involves several conversions which take place in the animals skin. The conversion of provitamin D (7-dehydrocholesterol) to previtamin D. This reaction is light (UVB) dependent. Previtamin D is converted into D3 (cholecalciferol) by a heat dependent reaction.
This means that if the animal cannot reach its optimum body temperature, it cannot synthesise vitamin D3 which is vital for calcium absorption.

Originally Posted by ToxicSiren

When the calcium levels are pretty low the body has to try take calcium from somewhere else to compensate for example the bones. This makes them softer making them easier to break and fracture. Calcium also impacts a number of other physiological systems including muscle contraction and blood clotting.

Calcium also plays a very important role in the nervous system controlling synaptic transmission.
The skeletal system is usually the first body system affected. When the muscular and nervous systems become affected, it is often too late to save the animal.

Originally Posted by ToxicSiren

Because reptiles dont absorb vitamin D that well they need ultraviolet light exposure to manufacture their own vitamin D.

This isn't really true.
As most lizard species have evolved to cope with a diet relatively low in D3 (insects and/or plants), they have no need to control the uptake of D3 through the gut. This makes over-supplementation (which can be just as dangerous as under-supplementation) a real danger.....
Too much D3 will result in hypercalcaemia (calcium levels in the blood become too high). This can lead to mineralisation of soft tissues.....the kidneys seem especially susceptible to this. The kidneys are vital for calcium absorption as they help convert D3 into an active hormone which directly controls calcium absorption from the gut. Renal failure can also result in hyperuricaemia (gout) which can also be very dangerous to individuals.

Originally Posted by ToxicSiren

Provide UVA and UVB for your reptiles

As already stated UVA is not necessary for D3 biosynthesis.


Hope you don't mind me adding to the thread. I feel that since this has been made a sticky, it should contain as much info. as possible....

[kevin d]

one person says one thing some one eles say other but from exsperance of a uvb bulb it does more good well worth having one if leo has mbd but iam no exspert just seen diffrence in my leo i only trn it on a few hours a day

[ToxicSiren]

Originally Posted by James D

I agree that this thread is a good idea, but there are a couple of things that could be added to it....


UVA does not control the biosynthesis of vitamin D3 at all as far as I'm aware, although UVB is very important.




Could you explain how this would cause MBD?
I've never heard of this being a cause and can't think how it would result in this disease...



Although low temps. will result in less efficient digestion, this is not why it can result in MBD.
The biosynthesis of vitamin D3 involves several conversions which take place in the animals skin. The conversion of provitamin D (7-dehydrocholesterol) to previtamin D. This reaction is light (UVB) dependent. Previtamin D is converted into D3 (cholecalciferol) by a heat dependent reaction.
This means that if the animal cannot reach its optimum body temperature, it cannot synthesise vitamin D3 which is vital for calcium absorption.



Calcium also plays a very important role in the nervous system controlling synaptic transmission.
The skeletal system is usually the first body system affected. When the muscular and nervous systems become affected, it is often too late to save the animal.



This isn't really true.
As most lizard species have evolved to cope with a diet relatively low in D3 (insects and/or plants), they have no need to control the uptake of D3 through the gut. This makes over-supplementation (which can be just as dangerous as under-supplementation) a real danger.....
Too much D3 will result in hypercalcaemia (calcium levels in the blood become too high). This can lead to mineralisation of soft tissues.....the kidneys seem especially susceptible to this. The kidneys are vital for calcium absorption as they help convert D3 into an active hormone which directly controls calcium absorption from the gut. Renal failure can also result in hyperuricaemia (gout) which can also be very dangerous to individuals.



As already stated UVA is not necessary for D3 biosynthesis.


Hope you don't mind me adding to the thread. I feel that since this has been made a sticky, it should contain as much info. as possible....

Lol dont mind at all, as stated on origional thread to add more info. Thanks for your input!

[fuzzielady]

For those that have been lucky enough not to see it. This is what a rubber jaw looks like in a crested gecko, second pic shows how her jaw should be

http://www.reptileforums.co.uk/gener...ect-not-3.html

And xrays showing severe MBD also (first 2 show MBD last one shows healthy bones)

http://www.reptileforums.co.uk/gener...ect-not-8.html